BALTIMORE — The tone of the game was set from the very beginning.
Derrick Henry took the ball on Baltimore's first offensive snap and ripped off a franchise-record 87 yard touchdown run. He and the Ravens never looked back, handing the Buffalo Bills their first loss of the season, 35-10.
The loss snaps the Bills streak of 43-straight regular season games of not losing by more than six points.
Josh Allen was pressured heavily throughout by the Baltimore defense.
The defense for the Bills (3-1) offered little resistance, giving up chunk plays to Henry and Justice Hill.
They look to bounce back next weekend when they head to Houston to face Stefon Diggs and the Texans.